Cannabis
European
We’re here for
healthcare professionals
We aim to provide all the educational materials about cannabis you need – from how quality is maintained in production, to how your patients may benefit. To do so, we work closely with Sapphire Medical, a company formed by doctors for the mutual benefit of patients and healthcare professionals.
Current guidelines
for medical cannabis
Follow the links below for the current best practice guidance from key medical associations in the UK:
Real world evidence
of medical cannabis
The future of cannabis is centred on personalised medicine, which requires a data-driven, real world approach to clinical decision making. Sapphire Medical is collecting real world evidence in a National Registry to bridge the gaps in medical knowledge to provide a comprehensive insight into the therapeutic benefits and applications of medical cannabis.
This free National Registry has been seamlessly integrated into the patient pathway and is capturing key data including efficacy, safety and patient-reported outcomes.
Publications and
abstracts
The increase of published scientific articles is bolstering the growth of medical cannabis. Below are some of the latest advances:
Erridge S, Salazar O, Kawka M, Holvey C, Coomber R, Usmani A, Sajad M, Beri S, Hoare J, Khan S, Weatherall MW, Platt M, Rucker JJ, Sodergren MH. An initial analysis of the UK Medical Cannabis Registry: Outcomes analysis of first 129 patients. Neuropsychopharmacol Rep. 2021 May 14. doi: 10.1002/npr2.12183. Epub ahead of print. PMID: 33988306
U Anand, B Pacchetti, P Anand, M H Sodergren. Cannabis-based medicine and pain: a review of potential synergistic and entourage effects. Pain Management 2021, 11(4):395-403. doi: 10.2217/pmt-2020-0110
S Hammond, S Erridge, N Mangal, B Pacchetti, M H Sodergren. The Effect Of Cannabis-Based Medicine In The Treatment Of Cachexia: A Systematic Review And Meta-Analysis. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
S Erridge, N Mangal, B Pacchetti, M H Sodergren. Cannflavins – From plant to patient: a scoping review. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Mangal N, Lawrence P, Ragulan C, Desai C, Pacchetti B, Reebye V, Sadanandam A, Sodergren MH. Therapeutic Effect of Cannabidiol in Combination with Chemotherapy in Pancreatic Ductal Adenocarcinoma. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Erridge S, Salazar O, Kawka M, Holvey C, Coomber R, Usmani A, Sajad M, Beri S, Hoare J, Khan S, Weatherall MW, Platt M, Rucker JJ, Sodergren MH. An Initial Analysis of the UK Medical Cannabis Registry. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Ergisi M, Erridge S, Harris M, Kawka M, Nimalan D, Salazar O, Loupasaki K, Ali R, Holvey C, Coomber R, Usmani A, Sajad M, Beri S, Hoare J, Khan S, Weatherall MW, Platt M, Rucker JJ, Sodergren MH. An Updated Analysis of General Clinical Outcome Measures Across Patient Groups in the UK Medical Cannabis Registry. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Ergisi M, Erridge S, Harris M, Kawka M, Nimalan D, Salazar O, Loupasaki K, Ali R, Holvey C, Coomber R, Platt M, Rucker JJ, Sodergren MH. UK Medical Cannabis Registry: An Analysis of Clinical Outcomes of Medicinal Cannabis Therapy for Anxiety. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Harris M, Erridge S, Ergisi M, Nimalan D, Nimalan D, Salazar O, Ali R, Loupasaki K, Ali R, Holvey C, Coomber R, Usmani A, Sajad M, Rucker JJ, Platt M, Sodergren MH. Exploring Quality of Life Outcomes of Chronic Pain Patients from The UK Medical Cannabis Registry. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Nimalan D, Kawka M, Erridge S, Ergisi M, Harris M, Salazar O, Loupasaki K, Ali R, Holvey C, Coomber R, Platt M, Rucker JJ, Khan S, Sodergren MH. Analysis of Palliative Care Patients from the UK Medical Cannabis Registry: Initial Experience and Outcomes. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Erridge S, Coomber R, Sodergren MH. Medical Cannabis, Over-The-Counter CBD And Public Opinion in the United Kingdom. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Mangal N, Reebye V, Pacchetti B, Sadanandam A, Sodergren MH. Ceramide synthase isoforms are upregulated by cannabidiol resulting in cytotoxic effect in pancreatic ductal adenocarcinoma. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Anand U, Pacchetti B, Anand P, Sodergren MH. Investigating cannabinoid entourage effects in cultured DRG neurons. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
F Marino, A Luini, M Legnaro, B Pacchetti, M H Sodergren, M Cosentino. Cannabidiol modulates human polymorphonuclear leukocyte functions: experimental evidence and clinical implications. Abstract and Oral communication – 19th Annual National Congress of the Italian Society of Neuroscience (SINS)
S Erridge, N Mangal, B Pacchetti, M H Sodergren. Cannflavins – From plant to patient: a scoping review. Fitoterapia Volume 146, October 2020, 104712 https://doi.org/10.1016/j.fitote.2020.104712
U Anand, B Jones, Y Korchev, S R Bloom, B Pacchetti, P Anand, M H Sodergren CBD Effect on TRPV1 Signaling Pathways in Cultured DRG Neurons. Journal of Pain Research 2020:13 2269–2278 2269 https://doi.org/10.2147/JPR.S258433
F Marino, M Legnaro, A Luini, B Pacchetti, M H Sodergren, M Cosentino. Cannabidiol inhibits cyclooxygenase expression and prostaglandin E2 production in human polymorphonuclear leukocites Presented and accepted at the 30th Annual International Cannabinoid Research Society Symposium on the Cannabinoids, ICRS Galway, July 2020
S Erridge, M Miller, T Gall, A Costanzo, B Pacchetti, M H Sodergren. A comprehensive patient and public involvement programme evaluating perception of cannabis-derived medicinal products in the treatment of acute postoperative pain, nausea and vomiting using a qualitative thematic framework. Cannabis and Cannabinoids Research 2020 Feb 27;5(1):73-80. doi: 10.1089/can.2019.0020
A Furgiuele, A M Tagne, B Pacchetti, M H Sodergren, M Cosentino, F Marino. Effect of Cannabidiol on Human Peripheral Blood Mononuclear Cell and Relevance for Immunomodulation in Multiple Sclerosis. Abstract and Poster IACM 10th Conference on Cannabinoids in Medicine.
Erridge S, Miller M, Gall T, Costanzo A, Pachetti B, Sodergren M. A comprehensive patient and public involvement programme evaluating perception of cannabis-derived medicinal products in the treatment of acute postoperative pain, nausea and vomiting using a qualitative thematic framework, Abstract and poster presentation at Emerald Conference, San Diego, USA 2019
We have
big plans
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