Cannabis science
We’re here for healthcare professionals
We aim to provide all the educational material about cannabis you need – from how quality is maintained in production, to how your patients may benefit. To do so, we are building a range of educational offerings across Europe – UK, Germany, Italy, Switzerland.
Get in touch for more information.
Current guidelines for medical cannabis
Follow the links below for the current best practice guidance from key medical associations in the UK:
Real world evidence of medical cannabis
The future of cannabis is centred on personalised medicine, which requires a data-driven, real world approach to clinical decision making. Curaleaf Clinic is collecting real world evidence in a National Registry to bridge the gaps in medical knowledge to provide a comprehensive insight into the therapeutic benefits and applications of medical cannabis.
This free National Registry has been seamlessly integrated into the patient pathway and is capturing key data including efficacy, safety and patient-reported outcomes.
Publications and abstracts
The increase of published scientific articles is bolstering the growth of medical cannabis. Below are some of the latest advances:
2023
Tait J, Erridge S, Sodergren MH. UK Medical Cannabis Registry: A Patient Evaluation. Journal of Pain and Palliative Care Pharmacotherapy. 2023. doi: https://doi.org/10.1080/15360288.2023.2174633
Nicholas M, Erridge S, Bapir L, Pillai M, Dalavaye N, Holvey C, Coomber R, Rucker JJ, Weatherall MW, Sodergren MH. UK Medical Cannabis Registry: Assessment of Clinical Outcomes in Patients with Headache Disorders. Expert Review of Neurotherapeutics. 2023. doi: https://doi.org/10.1080/14737175.2023.2174017
Bapir L, Erridge S, Nicholas M, Pillai M, Dalavaye N, Holvey C, Coomber R, Hoare J, Khan S, Weatherall MW, Rucker JJ, Platt MW, Sodergren MH. Comparing the Effects of Medical Cannabis for Chronic Pain Patients With and Without Co-Morbid Anxiety: A Cohort Study. Expert Review of Neurotherapeutics. 2023. doi: https://doi.org/10.1080/14737175.2023.2181696
Olsson F, Erridge S, Tait J, Holvey C, Coomber R, Beri S, Hoare J, Khan S, Weatherall MW, Platt MW, Rucker JJ, Sodergren MH. An observational study of safety and clinical outcome measures across patient groups in the United Kingdom Medical Cannabis Registry. Expert Review of Clinical Pharmacology. 2023. doi: https://doi.org/10.1080/17512433.2023.2183841
Tait J, Erridge S, Holvey C, Coomber R, Usmani A, Sajad M, Hoare J, Khan S, Weatherall M, Rucker JJ, Platt M, Sodergren MH. Clinical Outcome Data of Chronic Pain Patients Treated with Cannabis-Based Oils and Dried Flower from the UK Medical Cannabis Registry. Expert Review of Neurotherapeutics. 2023. doi: https://doi.org/10.1080/14737175.2023.2195551
Erridge S, Sodergren MH. Medical Cannabis and Neurological Disorders: A Clinical Overview. British Journal of Neuroscience Nursing. 2023. doi: https://doi.org/10.12968/bjnn.2023.19.Sup3.S30
Erridge S, Mangoo S, Sodergren MH. Reflections on the Future of Medical Cannabis Research for Depression. Expert Review of Neurotherapeutics. 2023. doi: https://doi.org/10.1080/14737175.2023.2203862
Kaur V, Erridge S, Sodergren MH, Rucker JJ. Medical cannabis and Attention-Deficit Hyperactivity Disorder. British Journal of Neuroscience Nursing. 2023. doi: https://doi.org/10.12968/bjnn.2023.19.2.65
Wang C, Erridge S, Holvey C, Coomber R, Usmani A, Sajad M, Guru R, Holden W, Rucker JJ, Platt MW, Sodergren MH. Assessment of clinical outcomes in patients with fibromyalgia: Analysis from the UK Medical Cannabis Registry. Brain and Behavior. 2023. doi: https://doi.org/10.1002/brb3.3072
Rifkin-Zybutz R, Erridge S, Holvey C, Coomber R, Gaffney J, Lawn W, Barros D, bhoskar U, Mwimba G, Praveen K, Symeon C, Sachdeva-Mohan S, Rucker JJ, Sodergren MH. Clinical outcome data of anxiety patients treated with cannabis-based medicinal products in the United Kingdom: a cohort study from the UK Medical Cannabis Registry. Psychopharmacology. 2023. doi: https://doi.org/10.1007/s00213-023-06399-3
Erridge S, Sodergren MH. Cannabis Use: A Marker of Clinical Severity in Inflammatory Bowel Disease? Inflammatory Bowel Diseases. 2023. doi: https://doi.org/10.1093/ibd/izad221
2022
Ergisi M, Erridge S, Harris M, Kawka M, Nimalan D, Salazar O, Loupasaki K, Ali R, Holvey C, Coomber R, Platt M, Rucker JJ, Sodergren MH. UK Medical Cannabis Registry: An Analysis of Clinical Outcomes of Medicinal Cannabis Therapy for Generalised Anxiety Disorder. Expert Review of Clinical Pharmacology. 2022. doi: https://doi.org/10.1080/17512433.2022.2020640
Harris M, Erridge S, Ergisi M, Nimalan D, Kawka M, Salazar O, Ali R, Loupasaki K, Holvey C, Coomber R, Usmani A, Sajad M, Rucker JJ, Platt M, Sodergren MH. UK Medical Cannabis Registry: An Analysis of Clinical Outcomes of Medicinal Cannabis Therapy for Chronic Pain Conditions. Expert Review of Clinical Pharmacology. 2021. doi: http://dx.doi.org/10.1080/17512433.2022.2017771
Ergisi M, Erridge S, Harris M, Kawka M, Nimalan D, Salazar O, Loupasaki K, Ali R, Holvey C, Coomber R, Usmani A, Sajad M, Beri S, Hoare J, Khan S, Weatherall MW, Platt M, Rucker JJ, Sodergren MH. An Updated Analysis of Clinical Outcome Measures Across Patients from the UK Medical Cannabis Registry. Cannabis and Cannabinoid Research. 2022. doi: https://doi.org/10.1089/can.2021.01451
Nimalan D, Kawka M, Erridge S, Ergisi M, Harris M, Salazar O, Ali R, Loupasaki K, Holvey C, Coomber R, Platt M, Rucker JJ, Khan S, Sodergren MH. UK Medical Cannabis Registry Palliative Care Patients Cohort: Initial Experience and Outcomes. Journal of Cannabis Research. 2022. doi: https://doi.org/10.1186/s42238-021-00114-9
Troup LJ, Erridge S, Ciesluk B, Sodergren MH. Perceived Stigma of Patients Undergoing Treatment with Cannabis-Based Medicinal Products. International Journal of Environmental Research and Public Health. 2022. doi: https://doi.org/10.3390/ijerph19127499
Erridge S, Sodergren MH, Weatherall M. Medical cannabis in multiple sclerosis. British Journal of Neuroscience Nursing. 2022. doi: https://doi.org/10.12968/bjnn.2022.18.Sup3.S28
Philipps E, Erridge S, Sodergren MH. Cannabis-based medicinal products: a clinical guide. British Journal of Neuroscience Nursing. 2022. doi: https://doi.org/10.12968/bjnn.2022.18.4.170
Erridge S, Kerr-Gaffney J, Holvey C, Coomber R, Barros D, Bhoskar U, Mwimba G, Praveen K, Symeon C, Sachdeva-Mohan S, Sodergren MH, Rucker JJ. Clinical Outcome Analysis of Patients with Autism Spectrum Disorder – Analysis from the UK Medical Cannabis Registry. Therapeutic Advances in Psychopharmacology. 2022 doi: https://doi.org/10.1177/20451253221116240
Erridge S, Sodergren MH, Rucker JJ. Medical cannabis in autism spectrum disorder: a specialist perspective. British Journal of Neuroscience Nursing. 2022. doi: https://doi.org/10.1177/20451253221116240
Erridge S, Coomber R, Sodergren MH. Medical Cannabis, CBD Wellness Products and Public Awareness of Evolving Regulations in the United Kingdom. Journal of Cannabis Research. 2022. doi: https://doi.org/10.1186/s42238-022-00165-6
Erridge S, Olsson F, Sodergren MH. Patient Priorities for Research: A Focus Group Study of UK Medical Cannabis Patients. Complementary Therapies in Clinical Practice. 2022. doi: https://doi.org/10.1016/j.ctcp.2022.101693
Pillai M, Erridge S, Bapir L, Nicholas M, Dalavaye N, Holvey C, Coomber R, Barros D, Bhoskar U, Mwimba G, Praveen K, Symeon C, Sachdeva-Mohan S, Rucker JJ, Sodergren MH. Assessment of clinical outcomes in patients with post-traumatic stress disorder: analysis from the UK Medical Cannabis Registry. Expert Review of Neurotherapeutics. 2022. doi: https://doi.org/10.1080/14737175.2022.2155139
Erridge S, Holvey C, Coomber R, Hoare J, Khan S, Platt MW, Rucker JJ, Weatherall MW, Beri S, Sodergren MH. Clinical Outcome Data of Children Treated with Cannabis Based Medicinal Products for Treatment Resistant Epilepsy – Analysis from the UK Medical Cannabis Registry. Neuropediatrics. 2022. doi: https://doi.org/10.1055/a-2002-2119
Dalavaye N, Erridge S, Nicholas N, Pillai M, Bapir L, Holvey C, Coomber R, Rucker JJ, Hoare J, Sodergren MH. The effect of medical cannabis in inflammatory bowel disease: analysis from the UK Medical Cannabis Registry. Expert Review of Gastroenterology and Hepatology. 2022. doi: https://doi.org/10.1080/17474124.2022.2161046
Mangoo S, Erridge S, Holvey C, Coomber R, Barros D, Bhoskar U, Mwimba G, Praveen K, Symeon C, Sachdeva-Mohan S, Rucker JJ, Sodergren MH. Assessment of clinical outcomes of medicinal cannabis therapy for depression: Analysis from the UK Medical Cannabis Registry. Expert Review of Neurotherapeutics. 2022. doi: https://doi.org/10.1080/14737175.2022.2161894
2021
Erridge S, Salazar O, Kawka M, Holvey C, Coomber R, Usmani A, Sajad M, Beri S, Hoare J, Khan S, Weatherall MW, Platt M, Rucker JJ, Sodergren MH. An initial analysis of the UK Medical Cannabis Registry: Outcomes analysis of first 129 patients. Neuropsychopharmacol Rep. 2021 May 14. doi: 10.1002/npr2.12183. Epub ahead of print. PMID: 33988306
U Anand, B Pacchetti, P Anand, M H Sodergren. Cannabis-based medicine and pain: a review of potential synergistic and entourage effects. Pain Management 2021, 11(4):395-403. doi: 10.2217/pmt-2020-0110
S Hammond, S Erridge, N Mangal, B Pacchetti, M H Sodergren. The Effect Of Cannabis-Based Medicine In The Treatment Of Cachexia: A Systematic Review And Meta-Analysis. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
S Erridge, N Mangal, B Pacchetti, M H Sodergren. Cannflavins – From plant to patient: a scoping review. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Mangal N, Lawrence P, Ragulan C, Desai C, Pacchetti B, Reebye V, Sadanandam A, Sodergren MH. Therapeutic Effect of Cannabidiol in Combination with Chemotherapy in Pancreatic Ductal Adenocarcinoma. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Erridge S, Salazar O, Kawka M, Holvey C, Coomber R, Usmani A, Sajad M, Beri S, Hoare J, Khan S, Weatherall MW, Platt M, Rucker JJ, Sodergren MH. An Initial Analysis of the UK Medical Cannabis Registry. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Ergisi M, Erridge S, Harris M, Kawka M, Nimalan D, Salazar O, Loupasaki K, Ali R, Holvey C, Coomber R, Usmani A, Sajad M, Beri S, Hoare J, Khan S, Weatherall MW, Platt M, Rucker JJ, Sodergren MH. An Updated Analysis of General Clinical Outcome Measures Across Patient Groups in the UK Medical Cannabis Registry. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Ergisi M, Erridge S, Harris M, Kawka M, Nimalan D, Salazar O, Loupasaki K, Ali R, Holvey C, Coomber R, Platt M, Rucker JJ, Sodergren MH. UK Medical Cannabis Registry: An Analysis of Clinical Outcomes of Medicinal Cannabis Therapy for Anxiety. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Harris M, Erridge S, Ergisi M, Nimalan D, Nimalan D, Salazar O, Ali R, Loupasaki K, Ali R, Holvey C, Coomber R, Usmani A, Sajad M, Rucker JJ, Platt M, Sodergren MH. Exploring Quality of Life Outcomes of Chronic Pain Patients from The UK Medical Cannabis Registry. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Nimalan D, Kawka M, Erridge S, Ergisi M, Harris M, Salazar O, Loupasaki K, Ali R, Holvey C, Coomber R, Platt M, Rucker JJ, Khan S, Sodergren MH. Analysis of Palliative Care Patients from the UK Medical Cannabis Registry: Initial Experience and Outcomes. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Erridge S, Coomber R, Sodergren MH. Medical Cannabis, Over-The-Counter CBD And Public Opinion in the United Kingdom. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Mangal N, Reebye V, Pacchetti B, Sadanandam A, Sodergren MH. Ceramide synthase isoforms are upregulated by cannabidiol resulting in cytotoxic effect in pancreatic ductal adenocarcinoma. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
Anand U, Pacchetti B, Anand P, Sodergren MH. Investigating cannabinoid entourage effects in cultured DRG neurons. Abstract ICRS 2021-The 31st Annual ICRS Symposium on the Cannabinoids
F Marino, A Luini, M Legnaro, B Pacchetti, M H Sodergren, M Cosentino. Cannabidiol modulates human polymorphonuclear leukocyte functions: experimental evidence and clinical implications. Abstract and Oral communication – 19th Annual National Congress of the Italian Society of Neuroscience (SINS)
2020
S Erridge, N Mangal, B Pacchetti, M H Sodergren. Cannflavins – From plant to patient: a scoping review. Fitoterapia Volume 146, October 2020, 104712 https://doi.org/10.1016/j.fitote.2020.104712
U Anand, B Jones, Y Korchev, S R Bloom, B Pacchetti, P Anand, M H Sodergren CBD Effect on TRPV1 Signaling Pathways in Cultured DRG Neurons. Journal of Pain Research 2020:13 2269–2278 2269 https://doi.org/10.2147/JPR.S258433
F Marino, M Legnaro, A Luini, B Pacchetti, M H Sodergren, M Cosentino. Cannabidiol inhibits cyclooxygenase expression and prostaglandin E2 production in human polymorphonuclear leukocites Presented and accepted at the 30th Annual International Cannabinoid Research Society Symposium on the Cannabinoids, ICRS Galway, July 2020
2019
S Erridge, M Miller, T Gall, A Costanzo, B Pacchetti, M H Sodergren. A comprehensive patient and public involvement programme evaluating perception of cannabis-derived medicinal products in the treatment of acute postoperative pain, nausea and vomiting using a qualitative thematic framework. Cannabis and Cannabinoids Research 2020 Feb 27;5(1):73-80. doi: 10.1089/can.2019.0020
A Furgiuele, A M Tagne, B Pacchetti, M H Sodergren, M Cosentino, F Marino. Effect of Cannabidiol on Human Peripheral Blood Mononuclear Cell and Relevance for Immunomodulation in Multiple Sclerosis. Abstract and Poster IACM 10th Conference on Cannabinoids in Medicine.
Erridge S, Miller M, Gall T, Costanzo A, Pachetti B, Sodergren M. A comprehensive patient and public involvement programme evaluating perception of cannabis-derived medicinal products in the treatment of acute postoperative pain, nausea and vomiting using a qualitative thematic framework, Abstract and poster presentation at Emerald Conference, San Diego, USA 2019
